Methylation is the passing of a chemical called a methyl group (a carbon atom linked to three hydrogen atoms) from one molecule to another. It is most easily understood by thinking of methylation as a domino series in your body.
The Methylation cycle is responsible for the function of:
The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase. This enzyme plays a role in processing amino acids, the building blocks of proteins. Methylenetetrahydrofolate reductase is important for a chemical reaction involving forms of the B-vitamin folate (also called folic acid or vitamin B9). Specifically, this enzyme converts 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate.
A single-nucleotide polymorphism (SNP, pronounced snip; plural snips) is a DNA sequence variation occurring when a single nucleotide — A, T, C or G — in the genome (or other shared sequence) differs between members of a biological species or paired chromosomes in a human(1).
Functions of Methylation:
- Epigenetics (Turns Genes On/Off)
- Protects and Stabilizes DNA
- Activates + Deactivates Stress Hormones
- Activates Serotonin, Melatonin and Dopamine
- Energy (ATP) Production
- Growth + Healing
- Autonomic Nervous System (ANS)
- Immune System
Methylation signs and Symptoms:
- Chronic Fatigue
- Sleep Disorders
- Inability to Adapt to Stress
- Toxic Encephalitis
- Genetic Disorders
- Hormone Dysregulation
What causes your Methylation to fail?
That is a fantastic question, there are many variables involved in a faulty Methlyation cycle, such as:
- Over consumption of Sugar
- Deficiency of B12=Folate
I hope you guys enjoyed todays post about Methylation and MTHFR.